Dolan FP

Ibuprofen

Relief of fever; mild to moderate aches & pains eg, dental pain including teething pain, toothache, muscular aches or soft tissue injuries including sprains & strains, headache, common cold, flu or sore throat; other types of pain eg, earache, or pain after vaccination or surgery; inflammation from juvenile RA. Susp/Forte susp: Relief of mild to moderate aches & pain eg, headache including migraine, neuralgia, muscular aches including minor arthritis pain, backache (including low back pain), dysmenorrhea; inflammation from arthritis, non-serious arthritic conditions.

Childn Usually 5-10 mg/kg/dose. All doses to be given every 6-8 hr as needed. Susp Childn 7-12 yr 10 mL, 3-6 yr 5-10 mL, 1-2 yr 5 mL. Forte susp Childn 7-12 yr 5 mL, 3-6 yr 2.5-5 mL, 1-2 yr 2.5 mL.

May be taken with or without food: May be taken w/ food or milk if stomach upset occurs.

Hypersensitivity to ibuprofen, aspirin or any other NSAIDs. Patients currently taking aspirin or other NSAIDs. Bronchospasm, angioedema, nasal polyps or allergic-type reactions after taking aspirin or other NSAIDs. Stomach ulcers, bleeding or other stomach problems eg, inflammatory bowel disease. Severe heart or liver; kidney (CrCl <30 mL/min) disease. Conditions involving increased tendency for active bleeding. Dehydration due to vomiting, diarrhea or lack fluids. SLE, dengue fever. Prior to or after undergoing heart surgery.

May cause a severe allergic reaction & stomach bleeding. Risk of heart attack or stroke. Prolonged use. Severe or persistent sore throat or sore throat accompanied by high fever, headache, nausea & vomiting. Heart problems, previous stroke or risk of high BP & cholesterol, diabetes, smoker; history of stomach problems eg, heartburn, Crohn's disease or ulcerative colitis; blood clotting disorder (eg, hemophilia); liver or kidney problems; asthma; connective tissue disease. Discontinue use if signs of stomach bleeding, allergic reaction or new symptoms occur; symptoms do not improve; redness or swelling in the painful area; no relief w/in 24 hr of treatment; pain worsens or lasts >10 days in adults or 3 days in childn. Concomitant use w/ diuretics. Renal impairment (especially in patients 12-18 yr who have not been drinking fluids or had lost fluids due to continuous vomiting or diarrhea). May affect ability to drive or operate machinery.

Constipation, decreased appetite, diarrhea, dizziness, dyspepsia, ear infection, fever, fluid retention, bloating or flatulence, headache, heartburn, indigestion, itching, mouth ulcers, nausea, nervousness, rash, tinnitus, sore throat, stomach cramps or pain, swelling, vertigo & vomiting.

May interfere w/ anti-platelet activity of aspirin limiting its cardioprotective effect. Increased risk of stomach & intestinal bleeding w/ phenylbutazone, indomethacin, salicylates (eg, aspirin) & other NSAIDs (eg, mefenamic acid, naproxen, diclofenac, ketoprofen), including COX-2 inhibitors (eg, celecoxib, etoricoxib); blood thinning medicines (eg, warfarin, dicumarol) or together w/ thrombolytic agents (eg, streptokinase); corticosteroids, SSRIs & anti-platelet agents. Increased toxicity of aminoglycosides (eg, amikacin, gentamicin, neomycin, tobramycin); lithium & methotrexate. Increased plasma levels w/ antacids eg, Mg hydroxide. Reduced effect of antihypertensives (eg, captopril, enalapril, losartan, telmisartan) & diuretics (eg, furosemide). May worsen heart failure, reduce kidney function & increase blood levels of cardiac glycosides (eg, digoxin). Reduced absorption w/ cholestyramine. Increased risk of kidney damage w/ ciclosporin & tacrolimus. Enhanced risk of bleeding w/ Gingko biloba. Altered safety & efficacy w/ medicines affecting liver enzymes. May increase plasma levels of sulfonylureas (eg, gliclazide, glipizide, glimepiride) & insulin. Increased toxicity by reduced metabolism & excretion w/ probenecid. Increased risk of convulsions w/ quinolones. Increased risk of blood problems eg, hemarthrosis & hematoma w/ zidovudine.

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

M01AE01 - ibuprofen ; Belongs to the class of propionic acid derivatives of non-steroidal antiinflammatory and antirheumatic products.

Non-Rx